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. 2010 Mar 15;285(19):14628–14638. doi: 10.1074/jbc.M110.117747

FIGURE 1.

FIGURE 1.

PA phosphatase reaction and its roles in lipid synthesis and signaling. The reaction catalyzed by PA phosphatase (highlighted) is shown. The reaction product DAG is used for the synthesis of triacylglycerol (TAG) and the synthesis of phosphatidylethanolamine (PE) or phosphatidylcholine (PC). The reaction substrate PA is used for the synthesis of phosphatidylinositol (PI) or phosphatidylglycerol (PG) via CDP-DAG. The substrate and product of the PA phosphatase reaction play roles in lipid signaling.