Table 1.
Baseline Characteristics by Medication Condition, Mean (SD) or n (%)
| Varenicline (2 mg/day) (n = 10) | Placebo (0 mg/day) (n = 10) | |
|---|---|---|
| Age | 34.20 (12.08) | 35.30 (12.71) |
| Sex (% male) | 80% | 80% |
| Race/Ethnicitya | ||
| Non-Hispanic White | 4 (40%) | 9 (90%) |
| Non-Hispanic Black | 4 (40%) | 0 (0%) |
| Hispanic | 2 (20%) | 1 (10%) |
| Education | ||
| ≤ High school | 4 (40%) | 5 (50%) |
| ≥ College | 6 (60%) | 5 (50%) |
| Marital Status | ||
| Not married | 7 (70%) | 9 (90%) |
| Married | 3 (30%) | 1 (10%) |
| Tobacco Use | ||
| Cigarettes per day | 21.23 (8.02) | 21.28 (8.73) |
| CO levels (ppm) | 27.70 (15.05) | 35.20 (12.44) |
| Urine cotinine (ng/mL) | 1629.10 (988.54) | 1648.10 (921.40) |
| FTND scoresb | 5.10 (1.60) | 5.30 (2.21) |
| Alcohol Use | ||
| Weekly frequency (days)c | 4.34 (1.63) | 4.01 (1.42) |
| Drinks per episodec | 8.04 (4.69) | 6.23 (3.42) |
| AUDIT scoresd | 10.30 (4.19) | 9.70 (4.37) |
| Current DSM-IV alcohol abuse | 5 (50%) | 4 (40%) |
| Lifetime DSM-IV alcohol abuse | 7 (70%) | 8 (80%) |
| Lifetime DSM-IV alcohol | ||
| Dependence | 4 (40%) | 2 (20%) |
AUDIT, Alcohol Use Disorders Identification Test; CO, breath carbon monoxide; FTND, Fagerström Nicotine Dependence.
a
p < .05 chi-square. Participants in the placebo group were more likely to be non-Hispanic White (χ2 = 6.26, p < .05).
b
Range: scores ≥ 4 for nicotine dependence.
c
Means calculated over 30 days before intake.
d
Scores ≥ 8 for alcohol misuse.