Table I.
PK Model Parameter Summary (n=6)
| V (ml/kg) | Vmax (mU/ml/h) | kma (mU/ml) | k12a (1/h) | k21a (1/h) | |
|---|---|---|---|---|---|
| Baseline (Mean (C.V.)) | 116 (19%) | 123 (52%) | 147 (93%) | 1.12 (53%) | 1.04 (61%) |
| Post-phlebotomy (Mean (C.V.)) | 128 (16%) | 161* (62%) | 147 (93%) | 1.12 (53%) | 1.04 (61%) |
Parameter shared at baseline and post-phlebotomy (see Data Analysis section for details).
Significantly different from baseline (p < 0.05).