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. Author manuscript; available in PMC: 2010 May 4.
Published in final edited form as: Pharm Res. 2007 Apr 25;24(9):1653–1659. doi: 10.1007/s11095-007-9295-3

Table I.

PK Model Parameter Summary (n=6)

V (ml/kg) Vmax (mU/ml/h) kma (mU/ml) k12a (1/h) k21a (1/h)
Baseline (Mean (C.V.)) 116 (19%) 123 (52%) 147 (93%) 1.12 (53%) 1.04 (61%)
Post-phlebotomy (Mean (C.V.)) 128 (16%) 161* (62%) 147 (93%) 1.12 (53%) 1.04 (61%)
a

Parameter shared at baseline and post-phlebotomy (see Data Analysis section for details).

*

Significantly different from baseline (p < 0.05).