TABLE 4.

Cytosolic and cell wall/membrane-associated proteins upregulated in the R clone L. sakei 23K-J30RO2^a

Protein type	Functional category	Function	Locus tag	ANOVAa	Fold vol change
Cytoplasm	Adaptation to atypical conditions	Chaperonin GroEL	LSA0359	0.017	2.7
		Chaperone protein DnaK	LSA1236	0.032	2.6
		Copper homeostasis protein (CutC)	LSA1440	0.018	1.5
	Transport and binding	H+-transporting two-sector ATPase (ATP synthase), gamma subunit	LSA1127	0.038	3.7
	Carbohydrate metabolism	6-Phosphofructokinase (Pfk)	LSA1033	0.044	2.5
	Transcription-translation	30S ribosomal protein S6 (RpsF)	LSA0007	0.025	2.1
		50S ribosomal protein L10 (RplJ)	LSA1667	0.046	2.0
	Translation	Cysteinyl tRNA synthase (CysS)	LSA1681	0.034	2.2
	Nucleotide metabolism	CTP synthase (PyrG)	LSA1629	0.041	3.2
		Xanthine phosphoribosyltransferase (Xpt)	LSA1557	0.021	1.6
Cell wall/membrane	Carbohydrate metabolization	l-Lactate dehydrogenase (l-Ldh)	LSA1606	0.007	1.5
	Nucleotide metabolism	CTP synthase (PyrG)	LSA1629	0.003	2.5
	Cell division	Cell shape-determining protein (MreB)	LSA0853	0.022	1.7
Surface exposed	Adaptation to atypical conditions	GTP-binding protein TypA	LSA1079	0.016	1.6
	Carbohydrate metabolism	Fructose-bisphosphate aldolase (Fba)	LSA1527	0.020	1.6
	Cell division	Cell shape-determining protein (MreB)	LSA0853	0.039	2.2

^aSee Table 3, footnote a.