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Survival of mice inoculated intraperitoneally with the Y. pseudotuberculosis Δhfq strain. Groups of 10 mice were inoculated by intraperitoneal injection with wild-type, Δhfq, or pYV− Y. pseudotuberculosis (103 CFU) and monitored for 21 days. Data are representative of two independent experiments; in one of the experiments, a single mouse infected with the Δhfq strain succumbed to the infection on day 11 (not shown).
