FIG. 3.
IL-4 regulation is associated with an increase in the number of lung DC. (A) Percentage of lung CD11c+ CD11b+ I-Abhi DC 7 days postinfection (n = 8 or 9). mat, matured (treated with LPS and anti-CD40). (B) Absolute number of lung DC at day 7 (n = 8 or 9). **, P < 0.001 compared to CCR2−/−. The data represent the means and SEM of two or three experiments. (C) Representative FACS plots of isolated lung leukocytes stained with CD11c and CD45.1 to identify transferred donor Ag-BMDC and Ag-free BMDC prior to infection (D0) and at days 1 (D1), 3 (D3), and 7 (D7) postinfection. CD45.1 transfer experiments were performed two times with three or four mice per group.