TABLE 4.
Number of yeast cells per phagocyte at day 7 of infection
Source of infected cells | No. of GFP+ yeast cells/phagocytea |
|||
---|---|---|---|---|
DCb | Tissue Mφb | Alveolar Mφb | Neutrophilsb | |
WT | 2.08 ± 0.14 | 1.90 ± 0.18 | 3.06 ± 0.25 | 1.48 ± 0.08 |
CCR2−/− | 3.19 ± 0.18c | 4.11 ± 0.57c | 3.00 ± 0.19d | 1.63 ± 0.10d |
The data are means ± SEM for at least 100 cells counted. The experiment was performed twice.
DC were CD11c+ CD11b+ I-Abhigh; tissue Mφ were CD11c− Mac-3+; alveolar Mφ were CD11c+ I-Abintermediate; and neutrophils were CD11c− CD11b+ Ly6-Ghigh.
P < 0.05.
P > 0.05.