FIG. 3.

Antibody responses against whole sporozoites in Spz-plus-CQ-immunized mice. Pooled sera from 5 mice immunized with either P. berghei, P. berghei[PyCS], or P. yoelii Spz plus CQ were tested by IFAT on P. berghei (top), P. berghei[PyCS] (middle), or P. yoelii (bottom) sporozoites to measure IgG (left) or IgM (right) reactivity. The titers correspond to the highest dilution of the pooled sera tested in duplicate that gave positive staining. BPL, below positivity level. The data are representative of two independent experiments with similar results.