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. 2010 Mar 1;78(5):2292–2301. doi: 10.1128/IAI.01186-09

FIG. 1.

FIG. 1.

S. Typhimurium infection in pregnancy. (a and b) Splenic bacterial burden in 129.B6F1 mice on day 3 after infection with 103 CFU of WT S. Typhimurium or the ΔinvA or ΔaroA mutant (a) or 106 CFU of S. Typhimurium ΔaroA (b). **, splenic bacterial burden in pregnant mice infected with WT S. Typhimurium or the ΔinvA mutant is significantly higher than that in the nonpregnant group by Mann-Whitney U test (P < 0.01). (c and d) Placental bacterial burden (c) and fetal resorption rates (d) on day 3 postinfection. Fetal resorption rates evoked by WT S. Typhimurium and S. Typhimurium ΔinvA are significantly higher than that for the noninfected pregnant group by Mann-Whitney U test; **, P < 0.001; *, P < 0.05. Each data point indicates individual mice, and the mean value for each group is indicated by a horizontal line.