Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Actinomycin biosynthetic gene cluster. The functions of the 28 genes that make up the gene cluster, including the 4 already known NRPS genes acmA to -D (66), are represented by arrows as follows: black, regulation; dark gray, 4-MHA biosynthesis; white, unknown role or function; gray, NRPS genes. In the lower part is shown the assembly line of the four NRPS subunits which catalyze the formation of 4-MHA pentapeptide lactone.
