TABLE 3.

Absence of cAM373-like activity in S. gordonii mutants

Culture filtrate straina	Titer using responder E. faecalisb
	OG1X/pAM373	OG1X/pAM4020
E. faecalis JH2-2	64-128	32-64
S. aureus 879R4RF	16-32	16
S. gordonii
CH1	16-32	8
CH1811	<2	<2
CH1967	<2	<2
CH1187	<2	<2
THB broth control	<2	<2

^aCulture filtrates were prepared as described in Materials and Methods.

^bBased on a microtiter dilution assay, the titer is the highest culture filtrate dilution factor still resulting in clumping of the responder. Titers are reported as the range in replicate tests (n ≥ 3). In this assay, a titer of 2 represents the lower limit of detection.