FIG. 7.
Rescue analysis in Tal1 knockout cells. Cell counts in MM precursors from SCLloxP/LacZ mice simultaneously transduced with MSCV-GFP-Cre and either a Tal1 or a Tal1T192P cDNA in the retroviral vector MSCV-IRES-YFP. GFP- and YFP-expressing cells were isolated by dual-color FACS. The Tal1T192P cDNA encodes a DNA binding-defective protein. Parental vector-transduced cells were used as controls, and the total number of cells per plate for each day is plotted. Each data point represents the mean ± the standard deviation from three plates of cells.