FIG. 1.
Inhibition of HIV-1 entry by HP-OVA as determined by time-of-addition assay. (A) HP-OVA (0.2 μM) was added to MT-2 cells at different intervals after infection with HIV-1IIIB. 3HP-ß-LG (0.2 μM), AZT (0.1 μM), AMD-3100 (0.2 μM), and T20 (0.5 μM) were included as controls. (B) HP-OVA (4.5 μM) was added to TZM-bl cells at different intervals after infection with HIV-1BaL. 3HP-ß-LG (4.5 μM), AZT (2 μM), maraviroc (0.2 μM), and T20 (2 μM) were included as controls. These assays were done in triplicate, and the experiment was repeated at least twice. Error bars indicate standard deviations.