TABLE 1.
Dosing scheme for intervention with sulfadoxime-pyrimethamine plus artesunate plus primaquinea
| Age (yr) | Weight (kg) (IQR)b | Gametocytocidal drug combination |
||
|---|---|---|---|---|
| Sulfadoxine (mg)/ pyrimethamine (mg) | Artesunate (mg) | Primaquine (mg) | ||
| 1-2 | 11.0 (9.5-11.6) | 250/12.5 | 25 | 7.5 |
| 3-4 | 12.9 (11.5-14.5) | 500/25 | 50 | 15 |
| 5-7 | 16.7 (14.8-19.0) | 500/25 | 75 | 15 |
| 8-11 | 23.0 (20.5-27.1) | 750/37.5 | 100 | 22.5 |
a
All individuals receiving placebo were given a dose of 1 tablet. Sulfadoxine-pyrimethamine and artesunate were administered at the nearest half tablet, and primaquine was administered as a combination of 7.5-mg and 15-mg tablets.
b
IQR, interquartile range (25th to 75th percentiles). The weights of different age groups were determined using previously published cross-sectional surveys of 2,752 inhabitants of the study population.