TABLE 2.
MIC values of several cephalosporins for E. coli 7014517, E. coli 8009162, E. coli ATCC 25922, and their corresponding recombinant clones
| Cephalosporin | MIC value (μg/ml) for strain |
||||||
|---|---|---|---|---|---|---|---|
| E. coli 7014517 (AmpC with LAA insertion at position 295) | E. coli Top10 producing AmpC 7014517 | E. coli 8009162 (AmpC with A292V mutation) | E. coli Top10 producing AmpC 8009162 | E. coli ATCC 25922 (wild-type AmpC) | E. coli Top10 producing AmpC 25922 | E. coli Top10 | |
| Ceftazidime | 64 | >256 | 64 | >256 | 0.09 | 4 | <0.06 |
| Cefotaxime | 16 | 32 | 8 | 12 | <0.06 | 0.75 | <0.06 |
| Cefepime | 8 | 4 | 0.75 | 0.75 | <0.06 | 0.06 | <0.06 |