TABLE 3.
Results of in vitro antimicrobial combinations with telavancin studied by time-kill assay at sub-MIC concentrations of both agents
| Phenotype | No of strainsa at 24 h showing synergy for telavancin tested in combination with: |
||||||
|---|---|---|---|---|---|---|---|
| Gentamicin | Ceftriaxone | Rifampin | Meropenem | Cefepime | Ciprofloxacin | Oxacillin | |
| All (n = 40) | 38 | 39 | 28 | 39 | 37 | 33 | 24 |
| VSSA (n = 27) | 27 | 27 | 20 | 27 | 26 | 24 | 12 |
| hVISA (n = 2) | 2 | 2 | 2 | 2 | 2 | 1 | 2 |
| VISA (n = 8) | 7 | 7 | 5 | 7 | 7 | 6 | 8 |
| VRSA (n = 3) | 2 | 3 | 1 | 3 | 2 | 2 | 2 |
a
No. of strains showing synergy at concentrations of comparator that were at or below the intermediate breakpoint are presented in the text.