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. 2010 Feb 16;54(5):1872–1877. doi: 10.1128/AAC.01636-09

TABLE 1.

Drug survival assays comparing strains F32-Tanzania and F32-ART

Drug Treatment duration (h)d Drug dose (μM) Time (days) to 5% parasitemiae
F32-Tanzania F32-ART
ARTa 48 9 16 ± 2f 6 ± 1.5
ART 48 18 17g 7 ± 1
ART 48 35 NGh 11 ± 2
ART 48* 70 NG 17
ART 96* 0.1 NG 15
ART 96* 1 NG 16
ATSb 48 2.6 14 ± 0.5 6 ± 0
ATS 48* 9 15 8
CQc 48 0.2 14 ± 0 14 ± 2
a

ART, artemisinin.

b

ATS, artesunate.

c

The dose tested corresponds to 10-fold the IC50 of chloroquine (CQ) for F32-Tanzania.

d

All experiments were carried out at least three times independently except those marked with an asterisk, which were carried out once.

e

Values express the time to reach 5% parasitemia in days ± standard deviations.

f

At day 21, two of three cultures recovered.

g

At day 21, only one of three cultures recovered.

h

NG, no growth at day 21.