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. 2010 Mar 1;54(5):1973–1980. doi: 10.1128/AAC.00870-09

TABLE 3.

Resistance-associated mutations in the RT polymerase domain derived from paired PR/RT RTVs

Patient sample RT mutation(s)
396a,b M41L, M184M/V, T215Y, K219R
471a,b M41L, D67D/N, Y181C, M184V, L210W, T215Y
440a,b M41L, M184V, L210W, T215Y
62a K103N, M184V, T215Y, P225P/H
477a,b M184V, T215Y
384a,b M184V
429b M41L, D67N, K70R, T215F, K219Q
58b M41L, A98A/G, K103N, Y181Y/C, G190G/A, L210W, T215Y
138b M41M/L, D67D/N, T215Y
87b M41L, L210W
474b M41L, D67N, K101E, Y181C, M184V, G190A, L210W, T215Y, K219N
249b M41L, D67N, M184V, G190G/A, T215H/Y, K219N
439b M41L, D67N, M184V, L210W, T215Y
442b M41L, D67N, T69D, L100I, K103N, M184V, L210W, T215Y, K219N
a

Patients with reduced susceptibility to DLV, EFV or NVP.

b

Patients with reduced susceptibility to ZDV.