TABLE 1.

MICs for all strains tested^a

Strain	Species	Country of origin	Yr isolated	Phenotype	MIC(μg/ml)				Reference
					PEN	CRO	CTX	CPT
1564b	S. pneumoniae	Romania	1996	PEN resistantc	16	32	32	2	32, 34
2688b	S. pneumoniae	Poland	2000	PEN resistantc	8	8	16	0.5	32, 34
1394b	S. pneumoniae	Slovakia	1999	PEN resistantc	4	2	4	0.25	32, 34
24	S. pneumoniae	South Africa	Before 1998	PEN resistantc	4	2	1	0.25	32, 34
3413	S. pneumoniae	Slovakia	2000	PEN resistantc	4	2	2	0.125	34
2527	S. pneumoniae	Croatia	2000	PEN resistantc	2	0.03	0.015	0.015	34
1076	S. pneumoniae	Austria	1996	PEN susceptiblec	0.03	0.03	0.03	0.015	34
ATCC 29213	S. aureus	Reference strain	1981	MSSA, VSSA	1	2	2	0.5	www.atcc.org
873	S. aureus	USA	2006	MRSA, hVISA, β-lactamase negative	8	>64	>64	0.5	33
510 (VRS2)	S. aureus	USA	2002	MRSA, VRSA, β-lactamase positive	32	>64	>64	1	4, 5
2149A	S. aureus	USA	2006	MRSA, VISA, linezolid resistant, β-lactamase positive	64	64	32	0.5	28
1287	S. aureus	USA	2007	MRSA, VISA, β-lactamase positive	32	8	4	0.5	33
25	S. aureus	USA	2005	MRSA, VISA, daptomycin resistant, β-lactamase positive	64	>64	>64	0.5	29

^aAbbreviations: PEN, penicillin G; CRO, ceftriaxone; CTX, cefotaxime; CPT, ceftaroline; MRSA, methicillin-resistant S. aureus; MSSA, methicillin-susceptible S. aureus; VRSA, vancomycin-resistant S. aureus; VISA, vancomycin-intermediate S. aureus; hVISA, heteroresistant vancomycin-intermediate S. aureus; VSSA, vancomycin-susceptible S. aureus.

^bNo demonstrable PBP binding affinity observed, except for PBP3.

^cClassified according to 2006 CLSI M100-S17 interpretive criteria (9).