FIG. 6.

Activity and selectivity of STAMPs against multispecies biofilms. Defined mixed-species biofilms of S. mutans and other oral streptococci were grown in 50% saliva prior to treatment with STAMP, parental AMP, or a commercial product. (A) Antimicrobial activity was calculated as the percentage of untreated S. mutans colony-forming units per milliliter or of total oral streptococci colony-forming units per milliliter recovered after treatment. (B) Selectivity was assessed as the ratio of surviving S. mutans bacteria to total oral bacteria. Data represent the averages of the results obtained with at least three independent experiments. *, fewer than 100 oral streptococci or S. mutans colony-forming units per milliliter detected.