TABLE 1.
Patient characteristics
| Characteristic | Description or valuea |
|---|---|
| General characteristics | |
| Sex (no. of males/no. of females) | 18/19 |
| Primary diagnosis (n [% of patients | |
| with diagnosis]) | |
| Meconium aspiration syndrome | 17 (46) |
| Congenital diaphragmatic hernia | 8 (22) |
| Pulmonary hypertension (other causes) | 5 (14) |
| Congenital heart defects | 4 (11) |
| Other (sepsis, viral infections, etc.) | 3 (7) |
| Body wt (kg) | 3.5 (2.0-6.2) |
| Gestation (wk) | 37 (3442) |
| Postnatal age at start of ECMO (days) | 3.3 (0.67-199) |
| Survival (no. of survivors/no. who did | |
| not survive) | 25/12 |
| Cefotaxime dose (intravenous) (n [%]) | |
| 50 mg/kg b.i.d. | 24 (65) |
| 50 mg/kg t.i.d. | 7 (19) |
| 37.5 mg/kg q.i.d. | 3 (8) |
| 25 mg/kg b.i.d. | 2 (5) |
| 37.5 mg/kg t.i.d. | 1 (3) |
| Serum chemistry | |
| Albumin (g/liter) | 31 (21-40) |
| Serum creatinine (μmol/liter) | 32 (19-69) |
| Aspartate amino transferase (IU/liter) | 44 (14-369) |
| Alanine aminotransferase (IU/liter) | 10 (0.5-40) |
| ECMO characteristics | |
| ECMO modality (n [%])b | |
| Venovenous (VV) | 22 (54) |
| Venoarterial (VA) | 19 (46) |
| Median ECMO flow (ml/kg/min) | 308 (50-530) |
| Duration of ECMO (h) | 108 (16-374) |
| No. of patients undergoing CVVH/no. of | |
| patients not undergoing CVVH | 30/7 |
| CVVH flow (ml/min) | 193 (100-350) |
| Body temp (no. of patients) | |
| Hypothermic (24°C) | 2 |
| Normothermic (36°C) | 35 |
a
Unless indicated otherwise, parameters are expressed as medians (ranges).
b
Four patients had 2 ECMO runs each: 3 VV + VA and 1 VA + VV.