TABLE 1.
Characteristic | Description or valuea |
---|---|
General characteristics | |
Sex (no. of males/no. of females) | 18/19 |
Primary diagnosis (n [% of patients | |
with diagnosis]) | |
Meconium aspiration syndrome | 17 (46) |
Congenital diaphragmatic hernia | 8 (22) |
Pulmonary hypertension (other causes) | 5 (14) |
Congenital heart defects | 4 (11) |
Other (sepsis, viral infections, etc.) | 3 (7) |
Body wt (kg) | 3.5 (2.0-6.2) |
Gestation (wk) | 37 (3442) |
Postnatal age at start of ECMO (days) | 3.3 (0.67-199) |
Survival (no. of survivors/no. who did | |
not survive) | 25/12 |
Cefotaxime dose (intravenous) (n [%]) | |
50 mg/kg b.i.d. | 24 (65) |
50 mg/kg t.i.d. | 7 (19) |
37.5 mg/kg q.i.d. | 3 (8) |
25 mg/kg b.i.d. | 2 (5) |
37.5 mg/kg t.i.d. | 1 (3) |
Serum chemistry | |
Albumin (g/liter) | 31 (21-40) |
Serum creatinine (μmol/liter) | 32 (19-69) |
Aspartate amino transferase (IU/liter) | 44 (14-369) |
Alanine aminotransferase (IU/liter) | 10 (0.5-40) |
ECMO characteristics | |
ECMO modality (n [%])b | |
Venovenous (VV) | 22 (54) |
Venoarterial (VA) | 19 (46) |
Median ECMO flow (ml/kg/min) | 308 (50-530) |
Duration of ECMO (h) | 108 (16-374) |
No. of patients undergoing CVVH/no. of | |
patients not undergoing CVVH | 30/7 |
CVVH flow (ml/min) | 193 (100-350) |
Body temp (no. of patients) | |
Hypothermic (24°C) | 2 |
Normothermic (36°C) | 35 |
Unless indicated otherwise, parameters are expressed as medians (ranges).
Four patients had 2 ECMO runs each: 3 VV + VA and 1 VA + VV.