TABLE 5.
CEM-101 drug interaction (synergy) results for five antimicrobial agents tested against S. aureus, S. pyogenes, and S. pneumoniaea
| Agent used in combination with CEM-101 | No. of isolates in the following interactive category: |
|||||
|---|---|---|---|---|---|---|
| Synergy |
Additive | Indifferent | Antagonism | Indeterminate | ||
| Complete | Partial | |||||
| Ceftriaxone | 0 | 2 | 5 | 12 | 0 | 3 |
| Gentamicin | 2 | 2 | 4 | 14 | 0 | 0 |
| Levofloxacin | 0 | 0 | 3 | 19 | 0 | 0 |
| Trimethoprim-sulfamethoxazole | 0 | 2 | 4 | 16 | 0 | 0 |
| Vancomycin | 0 | 1 | 6 | 15 | 0 | 0 |
a
Nine S. aureus strains, six S. pyogenes strains, and seven S. pneumoniae strains were tested.