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Therapeutic efficacy of antituberculars against H37Rv in vivo. B6 mice were infected by intratracheal instillation with 105 CFU H37Rv per mouse. The mice were treated with antituberculars orally once a day from day 1 to day 8. Data are the means ± SDs of the log10 CFU/lung of five mice per time point. The dashed line indicates the log10 CFU/lung at the ED99.
