TABLE 1.
Analysis of global histone methyl modifications in dUTX mutantsa
| Histone modification | Change of methylation pattern |
|---|---|
| H3K4me1 | Downregulated in dUTX clones |
| H3K4me2 | − |
| H3K4me3 | − |
| H3K9me1 | − |
| H3K9me3 | − |
| H3K27me1 | − |
| H3K27me2 | − |
| H3K27me3 | Upregulated in dUTX clones |
| H3K36me1 | − |
| H3K36me3 | − |
| H3K79me1 | − |
| H3K20me1 | − |
a
Antibodies specific for the indicated histone methyl modifications were tested in dUTX mosaic eye imaginal discs. Only global levels of H3K4me1 and H3K27me3 were altered in dUTX mutant clones (Fig. 2). − indicates no change in the histone methylation pattern compared to that of the wild type.