TABLE 2.

Constant infectivity model: estimated parameter values^a

Animal groupb	T0 (cells/μl)	β̄ (10−8 ml/RNA/day)	δ (1/day)	d (1/day)	SSR
Group 1
25479	131.4 (65.7-557.7)	1.18 (0.32-2.62)	0.19 (0.05-0.43)	0.03 (0.007-0.08)	0.176
25948	14.9 (5.4-37.3)	9.80 (4.35-28.67)	0.25 (0.21-0.33)	0.002 (0.001-0.003)	0.159
29459	139.1 (119.6-169.5)	1.10 (0.93-1.29)	0.35 (0.30-0.36)	0.018 (0.018-0.022)	0.030
29271	101.2 (77.5-138.3)	1.62 (1.24-2.17)	0.20 (0.19-0.22)	0.001 (0.001-0.002)	0.028
27361	10.5 (6.6-14.4)	15.63 (11.33-23.77)	0.12 (0.11-0.14)	0.002 (0.001-0.003)	0.099
29029	43.1 (32.0-63.2)	3.61 (2.49-4.73)	0.18 (0.15-0.24)	0.009 (0.007-0.015)	0.022
26811	21.3 (11.1-45.2)	4.24 (1.60-6.20)	0.20 (0.09-0.29)	0.008 (0.003-0.029)	1.141
25908	14.1 (7.6-28.0)	9.81 (5.1-17.7)	0.21 (0.15-0.26)	0.003 (0.002-0.004)	0.095
Mean	59.4	5.87	0.21	0.009
Median	32.2	3.92	0.20	0.005
Group 2
35036	88.9 (29.1-846.7)	2.12 (0.19-5.43)	0.22 (0.13-0.33)	0.002 (0.001-0.003)	0.497
33815	40.3 (19.7-88.4)	3.29 (1.37-6.03)	0.19 (0.11-0.29)	0.009 (0.004-0.014)	0.185
36068	24.2 (2.6-53.8)	4.95 (2.04-41.80)	0.27 (0.18-0.41)	0.002 (0.001-0.004)	0.163
Mean	51.1	3.45	0.23	0.004
Median	40.3	3.29	0.22	0.002
Group 3
34373	64.8 (26.4-264.6)	1.96 (0.62-4.05)	0.30 (0.06-1.47)	0.061 (0.001-0.21)	0.095
33952	37.2 (17.4-80.0)	3.45 (1.50-6.63)	0.25 (0.17-0.41)	0.007 (0.003-0.011)	0.134
34846	19.5 (19.5-19.5)	4.47 (4.47-4.47)	0.23 (0.23-0.23)	0.007 (0.007-0.007)	0.047
Mean	40.5	3.29	0.26	0.025
Median	37.2	3.45	0.25	0.007
Overall mean	53.6 (30.39-76.8)	4.80 (2.62-6.98)	0.23 (0.20-0.25)	0.011 (0.003-0.020)
Overall median	38.7	3.53	0.22	0.007

^aThe estimated parameter values T₀, β̄ (constant infection rate), δ, d, and sum of squared residuals (SSR) for the eight donor animals, three ramp-up plasma recipient animals, and three set-point plasma recipient animals are indicated (26). Numbers in parentheses indicate the 95% CI.

^bSee Table 1, footnote b.