FIG. 7.

CVS infection diminishes total axonal outgrowth in DRG cultures. Assessment of axonal outgrowth in CVS-infected (black bars) and mock-infected (white bars) DRG cultures assessed by using the number of intersects per neuron (n = total of 98 neurons for CVS infection and 66 neurons for mock infection). There was no significant difference at 24 h p.i. (P = 0.10), but there was a highly significant (**) 42% reduction (167 ± 22 versus 97 ± 9) at 48 h p.i. (P = 0.008) and 60% reduction (149 ± 26 versus 60 ± 5) in axonal growth at 72 h p.i. (P = 0.003) in mock-infected neurons versus CVS-infected neurons. Error bars represent SEM.