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Comparison of genotype 1a, 1b, 2a, 3a, 4a, 5a, and 6a NS3 protease and NS4A cofactor sequences. (A) Alignment of NS3 protease residues (in black) from recombinants J1a1a, J1b1b, J2a2a, J3a3a, J4a4a, J5a5a, and J6a6a to JFH1 (NCBI accession no. AB047639). (B) Alignment of NS4A protease cofactor residues (in black) from recombinants J1a1a, J1b1b, J2a2a, J3a3a, J4a4a, J5a5a, and J6a6a to JFH1. Dots indicate amino acid sequence identity.
