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J1b1b, J3a3a, J4a4a, and J6a6a study subject-derived protease recombinants and their viability in Huh7.5 cells. The protease region of J1b1b, J3a3a, J4a4a, and J6a6a was replaced with that of two or three study subject-derived protease genes, and their replication capacities were assessed in the Huh7.5 cells.
