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. 2010 Mar 10;84(10):5097–5107. doi: 10.1128/JVI.02169-09

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FIG. 1. — Terminal lymphoid and brain (medulla at obex) IHC analysis results of naïve deer cohorts inoculated with CWD⁺ blood components. PrP^CWD demonstrated by IHC analysis in tonsil, brain (medulla oblongata at obex), and retropharyngeal lymph node tissues of deer receiving whole blood, cell fraction, B cells, or CD41/61⁺ cells from CWD-infected donors. Arrows indicate PrP^CWD staining (red) within the brain and lymphoid follicles. The arrow with the asterisk indicates a lymphoid follicle negative for PrP^CWD.