TABLE 4.
Inhibition of pGTy1his3AI retrotransposition by A3G in mRNA decay mutants
| Genotype | Fold inhibition of pGTy1his3AI retrotransposition by A3Ga | Relative A3G inhibition (P value)b |
|---|---|---|
| WT | 36.6 | 1.00 |
| xrn1Δ | 15.3 | 0.42 (0.11) |
| dhh1Δ | 75.0 | 2.05 (0.94) |
| lsm1Δ | 35.9 | 0.98 (0.54) |
| upf1Δ | 5.9 | 0.16 (0.0015)c |
a
Ratio of the median pGTy1his3AI retrotransposition frequency in the strain carrying an empty vector to that in the strain expressing pGAL1-A3G.
b
Ratio of the fold inhibition in the deletion strain to the fold inhibition in the wild-type strain. P values shown are for a one-sided test to determine whether inhibition is reduced in the deletion strain.
c
The P value was <0.01 after controlling for FDR.