. 2010 Mar 3;84(10):5277–5293. doi: 10.1128/JVI.02667-09

TABLE 3.

Genetic heterogeneity of the ED43 virus population from chimpanzee acute-phase plasma pool

Genomic region	Genetic heterogeneity at the nucleotide level			Genetic heterogeneity at the amino acid level
	Nucleotide position^a	GH ≥1 clone^b		Amino acid position^a	GH ≥1 clone^b
	Nucleotide position^a	No.	%	Amino acid position^a	No.	%
5′UTR	28-340	6	1.9
Core	341-913	13	2.3	1-191	6	3.1
E1	914-1489	12	2.1	192-383	8	4.2
E2	1490-2578	19	1.7	384-746	7	1.9
HVR1	1490-1570	0	0	384-410	0	0
p7	2579-2767	5	2.6	747-809	3	4.8
NS2	2768-3418	11	1.7	810-1026	6	2.8
NS3	3419-5311	31	1.6	1027-1657	14	2.2
NS4A	5312-5473	4	2.5	1658-1711	2	3.7
NS4B	5474-6256	12	1.5	1712-1972	5	1.9
NS5A	6257-7591	12	0.9	1973-2417	3	0.7
NS5B	7592-9364	26	1.5	2418-3008	10	1.7
ORF	341-9364	145	1.6	1-3008	64	2.1

The nucleotide and amino acid positions refer to pED43.

GH ≥1 clone, genetic heterogeneity at the respective position found in at least one of the analyzed clones. The number and percentage (related to the respective genome region) of positions with genetic heterogeneity in the analyzed clones are shown. Defective genomes were not considered to reflect naturally occurring genetic heterogeneity and are not included in this analysis.