TABLE 1.
Summary of median centripetal and centrifugal amino acid substitution rates in different regions during the 3 years of transition from acute to chronic infection
| Time period (yr) | Median amino acid substitution rate by site and type (10−3 substitutions/site/year) |
|||||||
|---|---|---|---|---|---|---|---|---|
| Non-E1E2 |
E1E2 |
HVR1 |
E1E2-non-HVR1a |
|||||
| Centrifugal | Centripetal | Centrifugal | Centripetal | Centrifugal | Centripetal | Centrifugal | Centripetal | |
| 0-1 | 2.3 | 3.2 | 7.2 | 4.5 | 55.6 | 74.1 | 3.8 | 0.9 |
| 1-2 | 1.8 | 1.4 | 6.3 | 9.0 | 92.6 | 92.6 | 1.9 | 3.8 |
| 2-3 | 2.7 | 2.3 | 10.8 | 10.8 | 92.6 | 129.6 | 6.6 | 3.8 |
a
The region of E1E2 excluding the HVR1 region.