FIG. 4.

Infectivity of VSVΔG* pseudotyped with the single-amino-acid mutant GPs in the C-type lectin-expressing cells. (A) The names of the MARV GP mutants and the positions of substituted amino acids are shown in the schematic. The number of infectious units determined for each virus in Vero E6 cells are shown on the right. (B, C) The relative infectivities of the viruses in K562/hMGL (B) and K562/DC-SIGN (C) cells were determined, as described in the legend of Fig. 1. All experiments were done in triplicate, and average results and standard deviations are shown. Statistical significance was determined (compared to the infectivity of VSV-Musoke in each K562/hMGL or K562/DC-SIGN cell) by Student's t test. *, P < 0.05.