TABLE 1.
ELISA antibody titers against MCV, BKV, and LPV VLPsa
| Antibody (polyclonal mouse sera) | Sample no. | ELISA antibody titer |
||
|---|---|---|---|---|
| MCV (MKT-21) | BKV | LPV | ||
| Anti-MCV (MCC350) | 1 | 100 | 100 | 300 |
| Anti-MCV (MCC350) | 2 | 300 | 300 | 300 |
| Anti-MCV (MCC350) | 3 | 300 | 300 | 300 |
| Anti-MCV (MKT-21) | 4 | 145,800 | 600 | 1,350 |
| Anti-MCV (MKT-21) | 5 | 145,800 | 200 | 450 |
| Anti-MCV (MKT-21) | 6 | 145,800 | 500 | 450 |
| Anti-BKV | 7 | 450 | 2,700 | 450 |
| Anti-BKV | 8 | 450 | 5,400 | 150 |
| Anti-LPV | 9 | 500 | 200 | 40,500 |
| Nonimmunized | 10 | <100 | <100 | <100 |
a
Three serum samples were obtained from three mice immunized with MCC350 VP1 protein (samples 1 to 3), three from mice immunized with the MCV MKT-21 VP1 VLPs (samples 4 to 6), two from mice immunized with BKV VP1 VLPs (samples 7 and 8), and one with LPV VP1 VLPs (sample 9). Serum from a nonimmunized mouse was also investigated (sample 10).