Table 3.
Numbers (percentages) of new prescriptions of proton pump inhibitors and their clinical indications
| Year of study
|
|||||
|---|---|---|---|---|---|
| Clinical indication | 1991 (n=731) | 1992 (n=1400) | 1993 (n=1847) | 1994 (n=2573) | 1995 (n=2908) |
| Licensed indications | |||||
| Duodenal disease | 42 (5.7) | 86 (6.1) | 124 (6.7) | 264 (10.3) | 369 (12.7) |
| Gastric disease | 41 (5.6) | 71 (5.1) | 121 (6.6) | 191 (7.4) | 224 (7.7) |
| Ulcer unspecified | 18 (2.5) | 39 (2.8) | 30 (1.6) | 73 (2.8) | 66 (2.3) |
| Oesophagitis | 226 (31) | 287 (20.5) | 399 (21.6) | 433 (16.9) | 396 (13.6) |
| Hiatus hernia and reflux | — | — | 400 (21.6) | 455 (17.7) | 507 (17.4) |
| Subtotal | 327 (44.8) | 483 (34.5) | 1074 (58.1) | 1416 (55.1) | 1562 (53.7) |
| Unlicensed indications | |||||
| Hiatus hernia and reflux | 171 (23.4) | 351 (25.1) | — | — | — |
| Non-ulcer dyspepsia | 116 (15.9) | 314 (22.4) | 459 (24.9) | 664 (25.8) | 918 (31.6) |
| Non-specific abdominal pain | 29 (3.9) | 73 (5.2) | 67 (3.6) | 119 (4.6) | 141 (4.8) |
| Miscellaneous gastrointestinal disease | 88 (12.0) | 179 (12.8) | 247 (13.4) | 374 (14.5) | 287 (9.9) |
| Subtotal | 404 (55.2) | 917 (65.5) | 773 (41.9) | 1157 (44.9) | 1346 (46.3) |