TABLE 2.

GenoType MTBDRsl test results for the detection of resistance to aminoglycosides and cyclic peptide in 52 M. tuberculosis strains^a

No. of strains	Drug resistance phenotypeb				Sequencing data [nucleotide or amino acid change(s) or wt]				No. of strains with the following result by the MTBDRsl test:
	KAN	AMK	CAP	STR	rrs [nucleotide change(s) or wt]			RpsL (amino acid change or wt)	wt	Mutationc
					1400 region	510 region	912 region
8	R	R	R	R	A1401G	wt	wt	K43R		4 (ΔWT1, MUTA1401G)
					A1401G	wt	wt	K88R		2 (ΔWT1, MUTA1401G)
					A1401G	A513C	wt	wt		1 (ΔWT1, MUTA1401G)
					G1484T	wt	A907C	wt		1 (ΔWT2, MUTG1484T)
1	R	R	R	S	A1401G	wt	wt	wt		1 (ΔWT1, MUTA1401G)
1	R	R	S	S	A1401G	wt	wt	wt		1 (ΔWT1, MUTA1401G)
2	S	S	R	R	wt	wt	wt	wt	2
3	R	S	S	R	wt	wt	wt	wt	2
					wt	C516T	wt	wt	1
25	S	S	S	R	wt	wt	wt	wt	7
					wt	A513C	wt	wt	1
					wt	wt	wt	K43R	13
					wt	wt	wt	K88R	2
					wt	C516T	wt	wt	1
					wt	wt	A907C+wt	wt	1
12	S	S	S	S	wt	wt	wt	wt	12

^awt, wild-type.

^bAMK, amikacin; CAP, capreomycin; KAN, kanamycin; STR, streptomycin; R, resistant; S, susceptible.

^cΔWT, lack of hybridization with the wild-type probe (WT1 or WT2).