TABLE 3.
Cumulative number of serotypes detected in the 100 study specimens by four different methods
| Serotype(s) | No. of positive specimensa |
||||
|---|---|---|---|---|---|
| Totalb | BEPCR | DPCR | BEC | DC | |
| 6C | 10 | 9 | 8 (1) | 8 | 8 |
| 21 | 8 | 7 (3) | 6 (3) | 5 (1) | 3 |
| 15B/Cc | 7 | 5 (1) | 6 (2) | 4 (1) | 3 |
| 23A | 6 | 6 (1) | 4 | 6 (1) | 4 |
| 23B | 6 | 6 (1) | 4 | 5 (1) | 4 |
| 11A/Dd | 5 | 5 | 5 | 4 | 4 |
| 10A | 5 | 5 | 5 | 4 | 4 |
| 35A/35C/42 | 5 | 5 (1) | 5 (1) | 3 | 3 |
| 35B | 5 | 3 (1) | 4 (2) | 3 (2) | 1 |
| 10F/10C/33C | 4 | 4 (2) | 2 (2) | 0 | 0 |
| 15A/15F | 4 | 4 | 4 | 4 | 3 |
| 34 | 3 | 3 (1) | 3 (1) | 3 (1) | 1 |
| 17F | 2 | 2 (1) | 1 (1) | 2 (1) | 1 |
| 22F/22A | 2 | 1 | 2 (1) | 1 | 1 |
| 19A | 2 | 2 | 2 | 2 | 2 |
| 33F/33A/37 | 2 | 2 | 2 | 2 | 2 |
| 3 | 2 | 2 | 2 | 2 | 2 |
| 4 | 1 | 1 | 0 | 0 | 0 |
| 7F/7A | 1 | 1 | 1 | 1 | 1 |
| 12F/12A/44/46 | 1 | 1 | 1 | 1 | 1 |
| 16F | 1 | 1 | 0 | 0 | 0 |
| 20 | 1 | 1 | 0 | 0 | 0 |
| 31 | 1 | 1 | 0 | 0 | 0 |
| 35F/47 | 1 | 1 | 1 | 1 | 1 |
| Total no. of positive specimens | 59 | 59 | 56 | 58 | 50 |
| Total no. of serotype identifications | 78 | 68 | 61 | 49 | |
| Cumulative no. of serotypes identified | 24 | 20 | 19 | 19 | |
The number found in DC-negative specimens, if any, is provided in parentheses.
Cumulative number of pneumococcus-positive specimens that were positive by one or more of the four methods used for serotype identification.
Serotype 15B/15C is considered a single serotype for this work. In some instances, the DC or BEC approach identified either or both serotype 15B and serotype 15C. The BEPCR and DPCR methods were not capable of distinguishing serotypes 15B and 15C.
For the BEC and DC methods, the complex serospecificities corresponded to the first serotype listed (e.g., for 11A/D, serotype 11A). The PCR-based approaches used are not capable of resolving these serotypes.