TABLE 1.
Relative sensitivity and specificity of the LightCycler MRSA advanced test and the BD GeneOhm MRSA assay compared to those of directly plated culturea
| Site | Relative sensitivity |
Relative specificity |
||
|---|---|---|---|---|
| LightCycler MRSA advanced | BD GeneOhm MRSA | LightCycler MRSA advanced | BD GeneOhm MRSA | |
| 1 | 91.4 (32/35; 76.9-98.2) | 91.4 (32/35; 76.9-98.2) | 97.5b (197/202; 94.3-99.2) | 92.0b (184/200; 87.3-95.4) |
| 2 | 95.8 (46/48; 85.7-99.5) | 95.8 (46/48; 85.7-99.5) | 95.9c (301/314; 93.0-97.8) | 81.8c (257/314; 77.1-86.0) |
| 3 | 100.0 (13/13; 75.3-100.0) | 100.0 (13/13; 75.3-100.0) | 97.6 (245/251; 94.9-99.1) | 96.8 (243/251; 93.8-98.6) |
| 4 | 95.0 (76/80; 87.7-98.6) | 96.3 (77/80; 89.4-99.2) | 93.9 (185/197; 89.6-96.8) | 93.4 (183/196; 88.9-96.4) |
| 5 | 100.0 (11/11; 71.5-100.0) | 100.0 (11/11; 71.5-100.0) | 96.8 (243/251; 93.8-98.6) | 97.2 (243/250; 94.3-98.9) |
| Total | 95.2 (178/187; 91.1-97.8) | 95.7 (179/187; 91.7-98.1) | 96.4c (1,171/1,215; 95.2-97.4) | 91.7c (1,110/1,211; 90.0-93.2) |
a
Results are shown as percentage (no. of results/total no. of samples; 95% CI [%]). There were 1,402 valid LightCycler MRSA advanced test results and 1,398 valid BD GeneOhm MRSA test results.
b
Difference between relative specificity results is P = 0.024.
c
Difference between relative specificity results is P < 0.001.