TABLE 2.
Relative sensitivity and specificity of the LightCycler MRSA advanced test, the BD GeneOhm MRSA assay, and directly plated culture compared to those of enrichment culture
| Site | Relative sensitivityf |
Relative specificity |
||||
|---|---|---|---|---|---|---|
| LightCycler MRSA advanced | BD GeneOhm MRSA | Directly plated culture | LightCycler MRSA advanced | BD GeneOhm MRSA | Directly plated culture | |
| 1 | 83.3 (30/36; 67.2-93.6) | 83.3 (30/36; 67.2-93.6) | 86.1 (31/36; 70.5-95.3) | 96.5a (194/201; 93.0-98.6) | 91.0a,b (181/199; 86.1-94.6) | 98.0b (197/201; 95.0-99.5) |
| 2 | 87.9 (51/58; 76.7-95.0) | 86.2 (50/58; 74.6-93.9) | 81.0 (47/58; 68.6-90.1) | 97.3c (289/297; 94.8-98.8) | 82.5c,d (245/297; 77.7-86.6) | 99.7d (296/297; 98.1-100.0) |
| 3 | 81.3 (13/16; 54.4-96.0) | 81.3 (13/16; 54.4-96.0) | 81.3 (13/16; 54.4-96.0) | 97.6b (242/248; 94.8-99.1) | 96.8b (240/248; 93.7-98.6) | 100.0b (248/248; 98.5-100.0) |
| 4 | 97.5 (79/81; 91.4-99.7) | 96.3 (78/81; 89.6-99.2) | 95.1 (77/81; 87.8-98.6) | 95.4 (187/196; 91.5-97.9) | 93.8b (183/195; 89.5-96.8) | 98.5b (193/196; 95.6-99.7) |
| 5 | 78.6 (11/14; 49.2-95.3) | 78.6 (11/14; 49.2-95.3) | 78.6 (11/14; 49.2-95.3) | 96.8b (240/248; 93.7-98.6) | 97.2b (240/247; 94.2-98.9) | 100.0b (248/248; 98.5-100.0) |
| Total | 89.8 (184/205; 84.8-93.5) | 88.8 (182/205; 83.6-92.8) | 87.3 (179/205; 82.0-91.5) | 96.8c,e (1,152/1,190; 95.6-97.7) | 91.8c,d (1,089/1,186; 90.1-93.3) | 99.3d,e (1,182/1,190; 98.7-99.7) |
a
Difference between relative specificity results is P = 0.037.
b
Difference between relative specificity results is P < 0.05.
c
Difference between relative specificity results is P < 0.001.
d
Difference between relative specificity results is P < 0.001.
e
Difference between relative specificity results is P < 0.001.
f
Results are shown as percentage (no. of results/total no. of samples; 95% CI [%]).