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(A) Serum sensitivity of S. cerevisiae and C. albicans threonine pathway mutants and the S. cerevisiae thr1Δ gcn4Δ mutant. Strains were incubated in serum for the time designated, and 5-μl volumes of 10-fold dilutions were plated on YPD medium. (B) Time course for serum killing of S. cerevisiae thr1Δ mutants.
