Table 3.

Histologic features in biopsies from patients with recurrent iMN

Patient	Days after Tx	Indication for Biopsy	UP	GD	Light Microscopy				IF					Electron Microscopy			Stage
					Glomeruli	Spikes	Deposits	F/TA (%)	IgG	C3	IgA	IgM	C1q	SEDD	FPF/FPE (%)	TRI
1	6	Protocola	Neg	No	17	No	Yes	0	2+	1+	0	0	0	1+	40	0	1
2	13	GD	<0.5	Yes	3	No	No	0	1 to 2+	0	0	0	0	1+	95	0	1
3	11	GD	2+	Yes	18	No	No	0	2 to 3+	0 to 1+	0	0	0	ND	ND	ND	1
4	19	GD	3+	Yes	13	No	Yes	15	1+	1+	0	1+	0	ND	ND	ND	1
5	19	GD	380 mg	Yes	17	No	No	<5	2+	0	0	0	0	ND	ND	ND	1
6	53	GD	2+	Yes	24	No	No	<5	3+	0+	0	0	0	ND	ND	ND	1
7	104	GD	Trace	Yes	5	Yes	No	50	2 to 3+	0 to 1+	0	0	0	3+	90	0	1
8	414	GD/NRP	NRP	Yes	12	Yes	Yes	15	3+	1+	0	0	0	ND	ND	ND	2
9	599	GD/NRP	NRP	Yes	12	No	Yes	<5	3+	1+	0	0	0	1+	100	0	1
10	674	NRP	NRP	No	5	Yes	Yes	ND	3+	1+	0	0	0	2+	100	0	2
11	721	GD/NRP	NRP	Yes	9	Yes	Yes	20	3+	1 to 2+	0	0	0	ND	ND	ND	2
12	963	NRP	NRP	No	35	Yes	No	15	2 to 3+	1+	0	0	0	1 to 2+	95	0	2
13b	1203	NRP	NRP	No	14	Yes	Yes	15	0	0	0	0 to 1+	0	1	30	0	2
14	3545	NRP	NRP	No	14	No	Yes	15	3+	1+	0	0	0	1+	90	0	2
15	5497	NRP	NRP	No	12	Yes	Yes	10	2 to 3+	1+	0	0	0	1	Mild	0	2

FPF/FPE, foot process fusion/foot process effacement; F/TA, fibrosis and tubular atrophy; GD, graft dysfunction; ND, not done; NRP, nephrotic-range proteinuria; SEDD, subepithelial dense deposits; TRI, tubuloreticular inclusions; Tx, transplantation; UP, urinary protein.

^aPatient underwent ABO-incompatible renal transplantation.

^bIF negative probably because of the segmental nature of the MN in this patient, which was also noted in his native biopsy.