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. 2010 May;5(5):836–843. doi: 10.2215/CJN.08001109

Table 4.

ORs [95% CI] for quartile 4 versus quartile 1 of β-carotene, vitamin E, and folate intake and presence of MA (ACR 25 to 355 μg/mg) or eGFR decline ≥30%

MA (ACR 25 to 355 μg/mg) eGFR Decline ≥30%
Total β-carotene
    age-adjusted 0.99 [0.65, 1.49] 0.56 [0.41, 0.78]
    MVa + vitamin E + folate 1.07 [0.66, 1.72] 0.60 [0.42, 0.85]
Total vitamin E
    age-adjusted 1.19 [0.91, 1.76] 0.64 [0.47, 0.87]
    MVa + folate + β-carotene 1.57 [0.97, 2.57] 0.68 [0.47, 1.00]
Total folate
    age-adjusted 0.72 [0.48, 1.10] 0.70 [0.52, 0.95]
    MVa + vitamin E + β-carotene 0.78 [0.46, 1.34] 1.22 [0.80, 1.88]

MV, multivariable.

a

Adjusted for age, hypertension, BMI, diabetes, cigarette smoking, activity (mets/wk), and cardiovascular disease. MA models also adjusted for eGFR and angiotensin-converting enzyme inhibitor/angiotensin-type 2 receptor blocker medication use.