FIG. 2.

Anti-gp120 binding IgG subclass profiles in vaccinated individuals. (A) The D7324-based gp120-capture ELISA was used to assess anti-gp120 IgG endpoint titers in sera from 25 vaccinees or placebo recipients. The 20 samples in which anti-gp120 IgG could be detected and quantified were further assessed for IgG subclass titers. Each symbol represents the endpoint titer for one vaccinee; the horizontal bar is the median for the group. Nonresponders (titers <1.0 × 10²) are shown in the gray shaded area of the plot. (B–F) Correlations between IgG and IgG subclasses: r coefficients were calculated by Spearman's rank correlation.