(A) Hematoxylin- and eosin-stained images of UVB-irradiated mouse skin. Images are representative of results from 5 tissue samples. (B) Myricetin prevents UVB induction of increased mouse epidermal thickness. After mice were treated as described for Figure 1B, the dorsal skin was excised, sectioned, mounted onto slides, and stained with hematoxylin and eosin for measurement of epidermal thickness. Bars represent the mean thickness (μm) of epidermis from 5 animals (40 measurements/section). Results are shown as means ± S.E. (n = 5). The symbol (##) indicates a significant difference (p < 0.01) between the control group and the UVB-irradiated group. Asterisks (** and ***) indicate significant differences of p < 0.01 or p < 0.001, respectively, between the myricetin-treated and non-treated groups of irradiated mice.