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. Author manuscript; available in PMC: 2010 May 4.
Published in final edited form as: Alcohol Clin Exp Res. 2007 Apr;31(4):582–595. doi: 10.1111/j.1530-0277.2007.00342.x

Fig. 6.

Fig. 6

Acute and prophylactic effects of baclofen on reduced social interaction (SI) in rats repeatedly withdrawn from chronic 4.5% ethanol diet (ED). Rats were exposed to control diet (CD) throughout or 3 cycles of 5 days’ exposure to 4.5% ED. The rats exposed to ED were injected with vehicle (ED-Veh) or 2.5 mg/kg baclofen (ED-Bac2.5) 4 h into the first and second withdrawal or with 1.25 mg/kg baclofen (ED-Bac1.25) 4.5 h into the third withdrawal. Social interaction behavior and line crossings were recorded 5 h into withdrawal after the third ethanol exposure was stopped. Bars represent the means ± SEM. Groups with different letters are significantly different from each other (Tukey’s protected t-tests).