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. Author manuscript; available in PMC: 2010 May 4.
Published in final edited form as: Lancet. 2008 Mar 15;371(9616):923–931. doi: 10.1016/S0140-6736(08)60418-3

Table 2.

Laboratory-based and non laboratory-based models for predicting cardiovascular disease outcomes

Women (n=3349) Men (n=2837)


β SE HR p value β SE HR p value
Laboratory-based*

Age 3·702 0·226 40·527 <0·0001 3·444 0·180 31·27   <0·0001
Systolic blood pressure 1·842 0·260 6·310 <0·0001 1·706 0·247 5·507 <0·0001
Current smoker 0·551 0·083 1·735 <0·0001 0·547 0·072 1·728 <0·0001
History of diabetes 0·711 0·131 2·037 <0·0001 0·688 0·145 1·990 <0·0001
History of blood
pressure treatment
0·382 0·093 1·466 <0·0001 0·246 0·105 1·99   <0·0001
Total cholesterol 0·577 0·205 1·780   0·005 0·767 0·183 2·154   0·0191

Non-laboratory-based

Age 3·904 0·218 49·608 <0·0001 3·560 0·182 35·196 <0·0001
Systolic blood pressure 1·545 0·267 4·689 <0·0001 1·627 0·251 5·091 <0·0001
Current smoker 0·571 0·083 1·770 <0·0001 0·568 0·073 1·766 <0·0001
History of diabetes 0·649 0·130 1·914 <0·0001 0·641 0·145 1·898 <0·0001
History of blood
pressure treatment
0·367 0·092 1·443 <0·0001 0·220 0·105 1·246   0·037
Body-mass index 0·847 0·198 2·332 <0·0001 0·727 0·242 2·069   0·0026

HR=hazard ratio. β=beta coefficient.

*

C statistic (95% CI): 0·829 (0·813–0·845) for women; 0·784 (0·766–0·801) for men.

Natural logarithm of the continuous variable.

C statistic (95% CI): 0·831 (0·816–0·847) for women; 0·783 (0·765–0·800) for men.

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