Table 5.
Frequency of DBP genotypes: TB cases vs. controls
| Ethnic group, City | Cases / Controls | DBP genotype, n (%) | P | ||
|---|---|---|---|---|---|
| Gc2/2 | Gc2/1 | Gc1/1 | |||
| Gujarati, London | Cases (n=123) Controls (n=140) |
22 (17.9) 13 (9.3) |
60 (48.7) 59 (42.1) |
41 (33.3) 68 (48.5) |
0.04 |
| Xhosa, Cape Town | Cases (n=210) Controls (n=163) |
0 (0) 0 (0) |
20 (9.5) 14 (8.6) |
190 (90.5) 149 (91.4) |
0.86 |
| Cape Coloured, Cape Town |
Cases (n=71) Controls (n=19) |
3 (4.2) 0 (0) |
14 (19.7) 4 (21.1) |
54 (76.1) 15 (78.9) |
<0.99 |
| White, Rio | Cases (n=55) Controls (n=49) |
8 (14.5) 5 (10.2) |
20 (36.4) 23 (46.9) |
27 (49.1) 21 (42.9) |
0.56 |
| Mixed, Rio | Cases (n=44)* Controls (n=18) |
2 (4.5) 2 (11.1) |
12 (27.3) 6 (33.3) |
29 (65.9) 10 (55.6) |
0.64 |
| Black, Rio | Cases (n=31) Controls (n=11) |
1 (3.2) 0 (0) |
5 (16.1) 3 (27.3) |
25 (80.6) 8 (72.7) |
0.75 |
*
DBP genotype not assigned for one case (Hae III genotype hh, Sty I genotype Ss)