Table 6.

Difference between disease stages

Instrument	n	Stage III	Stage IV	p-value*
EQ-5D	231	0.73	0.68	0.180
VAS	243	52	45	0.009
SF-12 - SF-6D	173	0.62	0.56	0.003
SF-12 - PCS	141	30	30	0.599
SF-12 - MCS	141	47	41	0.007
SGRQ - total	234	63	69	0.008
SGRQ - symptoms	243	75	72	0.317
SGRQ - activity	240	78	85	0.008
SGRQ - impact	240	51	59	0.005

* from mixed linear regression adjusted for age, sex, smoking status and time of assessment

MCS: mental component score; PCS: physical component score.