Table 1.

Disease was reduced in EE treated WT and ERKO mice compared to their respective controls.

		CDI	Onset	Peak
WT:	Ctrl	64.5 (± 2.5)	12.3 (± 0.4)	5.1 (± 0.1)
	EE	54.0* (± 1.8)	12.0 (± 0.5)	4.8 (± 0.1)
ERKO:	Ctrl	60.5 (± 4.0)	11.7 (± 0.4)	4.8 (± 0.2)
	EE	48.5* (± 3.1)	12.2 (± 0.4)	4.2* (± 0.2)
GPR30KO:	Ctrl	47.6 (± 5.3)	11.5 (± 0.4)	4.5 (± 0.3)
	EE	51.2 (± 4.2)	11.0 (± 0.4)	4.6 (± 0.6)

Cumulative disease index (CDI) was reduced in EE-WT and EE-ERKO mice compared to their respective control groups. Peak disease severity was only reduced in ERKO-EE mice. Onset did not differ between any EE and control groups. * indicates p < .03