Table 1.
Examples showing alignment of mature sequences from miR-15 family members and non-family member with matching seeds
Family member | miRNA name | Mature sequence from 5' to 3' end |
---|---|---|
Family members with sequence identity in both the seed regiona and the 3' regionb | hsa-miR-15ac | UAGCAGCACAUAAUGGUUUGUG |
| | | | | | | | | | | | | | | | | | | ||
hsa-miR-15bc | UAGCAGCACAUCAUGGUUUACA | |
Family members with sequence identity in the seed regiona but very limited identity in the 3' regionb | hsa-miR-15ac | UAGCAGCACAUAAUGGUUUGUG |
| | | | | | | | | | | | | | | | | ||
hsa-miR-16c | UAGCAGCACGUAAAUAUUGGCG | |
Non-family members with sequence identity both in the seed regiona and in the 3' regionb | hsa-miR-15ac | UAGCAGCACAUAAUGGUUUGUG |
| | | | | | | | | | | | | | | | | | ||
hsa-miR-497d | CAGCAGCACACUGUGGUUUGU |
aBold and italicised.
bBold.
cMember of the miR-15 family.
dMember of the miR-497 family.